Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor used in the treatment method of various myeloma. Its synthesis or examine is essential for guaranteeing the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound in the synthesis of imatinib, a drug that targets precise forms of cancer, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the output approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in 5'-dibenzoate the remedy of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal cancer and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, which have several purposes, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Employed in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication employed to CAS NO. 848133-35-7 handle variety two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).